Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078214 | 0.89 | MAPT (0.33) | MAPTMEN1KMT2ACTSLCTSB | |
| SCHEMBL4100097 | 0.88 | CA2 (0.38) | MAPTMEN1KMT2AMMP2MMP3 | |
| SCHEMBL30989292 | 0.83 | MEN1 (0.38) | MAPTMEN1KMT2AACE2TP53 | |
| SCHEMBL10518210 | 0.83 | MEN1 (0.38) | MAPTMEN1KMT2AACE2TP53 | |
| SCHEMBL9044977 | 0.83 | MEN1 (0.36) | MAPTMEN1KMT2APPARG | |
| SCHEMBL1610399 | 0.80 | MEN1 (0.37) | MEN1KMT2APPARG | |
| SCHEMBL8075281 | 0.80 | MAPT (0.30) | MAPT | |
| SCHEMBL29399995 | 0.79 | CA1 (0.36) | MEN1KMT2ADPP7TP53CA2 | |
| SCHEMBL3988416 | 0.78 | CA1 (0.40) | MEN1KMT2ACA2 | |
| SCHEMBL8075279 | 0.76 | MAPT (0.34) | MAPTACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093345-A | PYRIMIDINE COMPOUNDS, ELECTROOPTICS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-07-25 | — | — | US | disclosed |