SCHEMBL9044977

SCHEMBL9044977

CCC[C@H](OC1CCCCO1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPARG P37231 4/20 0.33
PPARA Q07869 4/20 0.33
SLC6A3 Q01959 3/20 0.33
TDP1 Q9NUW8 2/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100097 0.91 CA2 (0.38) MEN1KMT2ASMN1; SMN2MAPTHPGD
SCHEMBL30989292 0.89 MEN1 (0.38) MEN1KMT2AMAPT
SCHEMBL10518210 0.89 MEN1 (0.38) MEN1KMT2AMAPT
SCHEMBL1610399 0.88 MEN1 (0.37) MEN1KMT2AALDH1A1PPARGPPARA
SCHEMBL29397787 0.87 ALDH1A1 (0.33) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL29087904 0.83 MEN1 (0.38) MEN1KMT2AALDH1A1SLC6A3ITGB1
SCHEMBL30638082 0.83 MEN1 (0.38) MEN1KMT2AALDH1A1SLC6A3ITGB1
SCHEMBL8064907 0.83 MAPT (0.36) MEN1KMT2AMAPTPPARG
SCHEMBL9345536 0.79 MEN1 (0.34) MEN1KMT2ASMN1; SMN2ALDH1A1SLC6A3
SCHEMBL10564764 0.79 MEN1 (0.33) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728752-A1 Triazole compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-08-28 EP disclosed
US-5405861-A Fungicides TAKEDA CHEMICAL INDUSTRIES, CO., LTD. (JP) 1995-04-11 US disclosed
US-5114615-A Compounds for optical apparatus WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-05-19 US disclosed
EP-0421210-A2 Triazole compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1991-04-10 EP disclosed