Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772534 | 0.81 | SMARCA2 (0.51) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL9891515 | 0.81 | L3MBTL1 (0.41) | SMARCA2SMARCA4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6633482 | 0.79 | SMARCA2 (0.50) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL5776103 | 0.79 | HTR2C (0.48) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL5834107 | 0.78 | SMARCA2 (0.47) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL14445424 | 0.78 | SMARCA2 (0.49) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL11129213 | 0.78 | SMARCA2 (0.49) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5409508 | 0.77 | SMARCA2 (0.46) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL11410175 | 0.76 | SMARCA2 (0.55) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 | |
| SCHEMBL11668320 | 0.75 | SMARCA2 (0.47) | SMARCA2SMARCA4HTR2CHTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005461-A1 | ACYLATED 5-AMINOISOTHIAZOLES AS PESTICIDES AND FUNGICIDES | Bayer Aktiengesellschaft (DE) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010334-A1 | ACYLATED 5-AMINOISOTHIAZOLES AS PESTICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-04 | — | — | WO | disclosed |