Diphenylether

Diphenylether

SCHEMBL8065401

C=C(C)C(=O)OCC(C)O.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
LMNA P02545 2/20 0.49
ALDH1A1 P00352 1/20 0.44
NPY5R Q15761 1/20 0.41
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
PTGS1 P23219 1/20 0.41
ELANE P08246 1/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ACACB O00763 1/20 0.40
ACACA Q13085 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
RAB9A P51151 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL8825712 0.84 LMNA (0.55) LMNAALDH1A1NPY5RMTNR1AMTNR1B
Styrene SCHEMBL5246216 0.84 TSHR (0.49) TSHRLMNAALDH1A1ELANEKDM4E
Diphenylsulfane SCHEMBL8053800 0.84 TSHR (0.49) TSHRLMNAALDH1A1MTNR1AMTNR1B
SCHEMBL11052821 0.83 POLB (0.50) LMNAMTNR1AMTNR1BTDP1POLB
SCHEMBL11465517 0.82 TSHR (0.47) TSHRLMNAALDH1A1MTNR1AMTNR1B
SCHEMBL8069892 0.82 TSHR (0.47) TSHRLMNAALDH1A1HTTNPC1
SCHEMBL9695772 0.82 TSHR (0.72) TSHRALDH1A1TDP1POLBAPEX1
SCHEMBL19017 0.82 TSHR (0.72) TSHRALDH1A1TDP1POLBAPEX1
SCHEMBL298588 0.82 POLB (0.53) TSHRLMNATDP1POLBAPEX1
SCHEMBL28299040 0.80 TSHR (0.45) TSHRLMNAALDH1A1MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US claimed
EP-0761604-B1 An agent for water treatment NIPPON CATALYTIC CHEM IND (JP) 2000-06-14 EP disclosed
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US disclosed
EP-0761604-A2 An agent for water treatment NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-12 EP disclosed