SCHEMBL8065623

SCHEMBL8065623

O=C(Oc1c(Cl)cccc1Cl)Oc1c(Cl)cccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
ALDH1A1 P00352 5/20 0.46
CAMK2A Q9UQM7 1/20 0.45
TSHR P16473 3/20 0.41
AKR1B1 P15121 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
PTPN7 P35236 1/20 0.39
PTPN12 Q05209 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
HPGD P15428 1/20 0.37
MEN1 O00255 2/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7553342 0.83 ALDH1A1 (0.50) KMT2AALDH1A1CAMK2ATSHRAKR1B1
SCHEMBL18697328 0.81 KMT2A (0.48) KMT2AALDH1A1CAMK2ATSHRAKR1B1
SCHEMBL3006462 0.81 KDM4E (0.48) KMT2AALDH1A1TSHRKDM4EHSD17B10
SCHEMBL29436765 0.79 ALDH1A1 (0.52) KMT2AALDH1A1CAMK2ATSHRAKR1B1
SCHEMBL9326165 0.79 KDM4E (0.47) KMT2AALDH1A1TSHRKDM4EHSD17B10
SCHEMBL2898218 0.76 KMT2A (0.48) KMT2AALDH1A1CAMK2AAKR1B1PTPN7
SCHEMBL28731525 0.76 KMT2A (0.44) KMT2AALDH1A1CAMK2ATSHRAKR1B1
SCHEMBL9161406 0.76 LMNA (0.50) KMT2AALDH1A1TSHRHDAC6HSD17B10
SCHEMBL15984565 0.75 NPC1 (0.40) KMT2AALDH1A1CAMK2AHPGD
SCHEMBL15984586 0.75 NPC1 (0.40) KMT2AALDH1A1CAMK2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1590287-A Carbon tube composite structure and preparation method thereof HAN CHIEN CHUNG (CN) 2005-03-09 CN disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
US-5225489-A Molding materials ALLIED-SIGNAL INC. (US) 1993-07-06 US disclosed
US-4980232-A RANDOM ORIENTED MIXTURE OF VARYING LENGTH AND DIAMETER ALLIED-SIGNAL INC. (US) 1990-12-25 US disclosed