Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29813419 | 1.00 | LMNA (0.49) | LMNAALDH1A1CYP3A4L3MBTL1TSHR | |
| SCHEMBL28232465 | 0.78 | LMNA (0.54) | LMNAALDH1A1L3MBTL1TSHREHMT2 | |
| SCHEMBL19268516 | 0.77 | ESR1 (0.59) | LMNAALDH1A1L3MBTL1TSHREHMT2 | |
| SCHEMBL17523062 | 0.77 | ESR1 (0.59) | LMNAALDH1A1L3MBTL1TSHREHMT2 | |
| SCHEMBL25620272 | 0.77 | ESR1 (0.59) | LMNAALDH1A1L3MBTL1TSHREHMT2 | |
| SCHEMBL12893200 | 0.77 | LMNA (0.54) | LMNAALDH1A1CYP3A4L3MBTL1TSHR | |
| SCHEMBL12893198 | 0.77 | LMNA (0.54) | LMNAALDH1A1L3MBTL1TSHREHMT2 | |
| SCHEMBL806949 | 0.77 | ESR1 (0.62) | LMNAALDH1A1CYP3A4L3MBTL1TSHR | |
| SCHEMBL14260413 | 0.76 | LMNA (0.52) | LMNAALDH1A1L3MBTL1TSHRESR1 | |
| SCHEMBL19863729 | 0.75 | ESR1 (0.58) | LMNAALDH1A1L3MBTL1TSHREHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |