Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979620 | 0.80 | KMT2A (0.51) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL8075519 | 0.80 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL7977790 | 0.79 | ALDH1A1 (0.47) | LMNANPC1RAB9AMAPTHPGD | |
| SCHEMBL8067282 | 0.79 | NPC1 (0.55) | SMN1; SMN2NPC1RAB9AHPGDKMT2A | |
| SCHEMBL8060900 | 0.78 | HPGD (0.40) | NPC1RAB9AHTTHPGDKMT2A | |
| SCHEMBL8082381 | 0.77 | HPGD (0.47) | LMNANPC1RAB9AMAPTHPGD | |
| SCHEMBL7978142 | 0.76 | ALOX5 (0.42) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7977366 | 0.76 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AMAPTMAOB | |
| SCHEMBL8051038 | 0.75 | MCHR1 (0.48) | LMNASMN1; SMN2MAPTHTTHPGD | |
| SCHEMBL8060916 | 0.75 | HPGD (0.51) | LMNANPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | disclosed |
| US-5952386-A | EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-14 | — | — | US | disclosed |