Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070297 | 0.95 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6248773 | 0.84 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8960845 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961233 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2HTR1AHTR1B | |
| SCHEMBL8961285 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8068508 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL8054334 | 0.82 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL8961109 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961222 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8065405 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155562-C | Novel naphthalene compounds, process for their preparation and pharmaceutical compositions containing them | ɪά��ʵ���� | 2004-06-30 | — | — | CN | disclosed |
| US-6143789-A | ENANTIOMORPHS | ADIR ET COMPAGNIE (FR) | 2000-11-07 | — | — | US | disclosed |
| EP-0919541-A1 | Naphthalene compounds, process for their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1999-06-02 | — | — | EP | disclosed |