Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GNG2 | P59768 | 4/20 | 0.35 |
| ▸ | GNB1 | P62873 | 4/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.34 |
| ▸ | CHAT | P28329 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065777 | 0.83 | PGAM1 (0.38) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL29945057 | 0.81 | PGAM1 (0.44) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL4875071 | 0.81 | PGAM1 (0.44) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL24631331 | 0.79 | TTR (0.47) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL9763220 | 0.78 | MAPT (0.52) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL8076779 | 0.76 | AURKA (0.39) | PGAM1MAPTLMNADAPK1MAPK1 | |
| SCHEMBL24631333 | 0.75 | TTR (0.47) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL28804762 | 0.72 | ALDH1A1 (0.50) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL27661265 | 0.72 | ALDH1A1 (0.50) | PGAM1TTRALDH1A1MAPTLMNA | |
| SCHEMBL1270794 | 0.71 | STAT3 (0.58) | PGAM1TTRALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6033826-A | POLYHYDROXYSTYRENE DERIVATIVE CONTAINING AN ACETAL OR KETAL GROUP WHICH CAN EASILY BE ELIMINATED IN THE PRESENCE OF AN ACID IN THE MOLECULE AND HAVING A VERY NARROW MOLECULAR WEIGHT DISTRIBUTION GIVES A RESIST MATERIAL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |