Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806585 | 0.78 | POLB (0.69) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL17340116 | 0.75 | KMT2A (0.58) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL24445724 | 0.74 | MAPT (0.66) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL31222507 | 0.74 | MAPT (0.66) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL2011023 | 0.73 | MEN1 (1.00) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL806582 | 0.71 | GAA (0.66) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL14192656 | 0.71 | KMT2A (0.82) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9468747 | 0.71 | KMT2A (0.82) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL12300221 | 0.71 | MEN1 (0.82) | POLBMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL16384054 | 0.70 | HTT (0.73) | POLBGAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |