Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806585 | 0.78 | POLB (0.69) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL16083225 | 0.73 | ALDH1A1 (0.65) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL10144715 | 0.73 | MEN1 (0.62) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL11228239 | 0.72 | HTT (0.67) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL24445724 | 0.72 | MAPT (0.66) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL31222507 | 0.72 | MAPT (0.66) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL806586 | 0.71 | POLB (0.77) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL195869 | 0.71 | MAPT (0.81) | GAAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL9312776 | 0.70 | GAA (0.84) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL18101781 | 0.69 | MAPT (0.77) | GAAMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2012037119-A2 | INHIBITORS OF VIRAL ENTRY INTO MAMMALIAN CELLS | MICROBIOTIX, INC. (US) | 2012-03-22 | — | — | WO | disclosed |