SCHEMBL8066253

SCHEMBL8066253

CCCCN(C#N)C(C)=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA9 Q16790 2/20 0.39
CES1 P23141 3/20 0.38
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
ZDHHC20 Q5W0Z9 3/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
ALDH1A1 P00352 3/20 0.32
CES2 O00748 3/20 0.32
TSHR P16473 1/20 0.32
ALDH2 P05091 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10647713 0.94 ZDHHC20 (0.41) CA12CA1CA9CES1ZDHHC20
SCHEMBL10881427 0.92 ZDHHC20 (0.44) CES1ZDHHC20ZDHHC2ALDH1A1CES2
SCHEMBL28451419 0.92 ZDHHC20 (0.44) CES1ZDHHC20ZDHHC2ALDH1A1CES2
SCHEMBL7620138 0.89 ZDHHC20 (0.31) ZDHHC20ZDHHC2
SCHEMBL10632860 0.86 ZDHHC20 (0.33) ZDHHC20ZDHHC2
SCHEMBL10953437 0.83 CA12 (0.39) CA12CA1CA9CES1MMP1
SCHEMBL10631655 0.79 ALDH1A1 (0.43) CA12CA1CA9CES1ALDH1A1
SCHEMBL8809998 0.79 ALDH1A1 (0.48) CA12CA1CA9CES1ALDH1A1
SCHEMBL8253430 0.77 ZDHHC20 (0.42) ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL5151350 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3262110-B1 IMPREGNATING RESINS WHICH ARE STABLE WHEN STORED AND ELECTRO ISOLATION TAPES SIEMENS ENERGY GLOBAL GMBH & CO KG (DE) 2023-03-29 EP disclosed
CN-107580615-B Storage-stable impregnating resin and electrical insulating tape 西门子公司 2020-07-21 CN disclosed
US-10479857-B2 Storage-stable impregnating resins and electrical insulating tapes SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US disclosed
US-20180171066-A1 STORAGE-STABLE IMPREGNATING RESINS AND ELECTRICAL INSULATING TAPES SIEMENS AKTIENGESELLSCHAFT (DE) 2018-06-21 US disclosed
EP-3262110-A1 STORAGE-STABLE IMPREGNATING RESINS AND ELECTRICAL INSULATING TAPES Siemens Aktiengesellschaft (DE) 2018-01-03 EP disclosed
WO-2016180595-A1 STORAGE-STABLE IMPREGNATING RESINS AND ELECTRICAL INSULATING TAPES SIEMENS AKTIENGESELLSCHAFT (DE) 2016-11-17 WO disclosed
EP-3091049-A1 IMPREGNATING RESINS WHICH ARE STABLE WHEN STORED AND ELECTRO ISOLATION TAPES Siemens Aktiengesellschaft (DE) 2016-11-09 EP disclosed
EP-1023302-A1 BINUCLEAR COMPLEX Lincoln, Per (SE) 2000-08-02 EP disclosed
WO-1999015535-A1 BINUCLEAR COMPLEX A+ SCIENCE INVEST AB (SE) 1999-04-01 WO disclosed
EP-0087393-B1 PROCESS FOR THE PREPARATION OF ISOMELAMINES, AND THEIR USE CIBA-GEIGY AG (CH) 1987-01-14 EP disclosed
EP-0087394-B1 PROCESS FOR THE PREPARATION OF N-SUBSTITUTED N-CYANO-AMIDES AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-14 EP disclosed
US-4550203-A REACTING AMIDE SALT WITH ALKYLATING AGENT CIBA GEIGY CORPORATION (US) 1985-10-29 US disclosed
US-4537946-A POLYEDOXIDE CURING AGENTS CIBA-GEIGY CORPORATION (US) 1985-08-27 US disclosed
US-4499268-A REACTING N-CYANO-N-(AR OR CYCLO)ALKYLCARBOXLIC AMINE WITH EITHER SODIUM(OR POTASSIUM) HYDROXIDE), AMINE, OR ALCOHOL CIBA GEIGY CORPORATION (US) 1985-02-12 US disclosed
EP-0087393-A2 Process for the preparation of isomelamines, and their use CIBA-GEIGY AG (CH) 1983-08-31 EP disclosed
EP-0087394-A2 Process for the preparation of N-substituted N-cyano-amides and their use CIBA-GEIGY AG (CH) 1983-08-31 EP disclosed