Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.44 |
| ▸ | HRH2 | P25021 | 6/20 | 0.40 |
| ▸ | HRH1 | P35367 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13026931 | 0.92 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2890587 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL3698390 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2900249 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2890590 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL3698393 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2900245 | 0.91 | GPR119 (0.43) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL8074091 | 0.91 | HRH2 (0.37) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2897872 | 0.90 | GPR119 (0.48) | GPR119HRH2HRH1KCNH2GPR183 | |
| SCHEMBL2898500 | 0.88 | GPR119 (0.49) | GPR119HRH2HRH1KCNH2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |