Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 10/20 | 0.37 |
| ▸ | HRH1 | P35367 | 10/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897630 | 0.92 | HRH2 (0.36) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL2897633 | 0.92 | HRH2 (0.36) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL8070582 | 0.92 | HRH2 (0.37) | HRH2HRH1F2RL3ACACBLMNA | |
| SCHEMBL13067274 | 0.92 | HRH2 (0.38) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL2891730 | 0.92 | HRH2 (0.38) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL2891733 | 0.92 | HRH2 (0.38) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL8066261 | 0.91 | GPR119 (0.44) | HRH2HRH1GPR119KCNH2F2RL3 | |
| SCHEMBL2899900 | 0.88 | GPR119 (0.40) | HRH2HRH1GPR119KCNH2GPR183 | |
| SCHEMBL2899896 | 0.88 | GPR119 (0.40) | HRH2HRH1GPR119KCNH2GPR183 | |
| SCHEMBL2897005 | 0.88 | GPR119 (0.40) | HRH2HRH1GPR119KCNH2GPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |