Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482084 | 0.74 | KMT2A (0.58) | KMT2AALDH1A1CHRNB2CHRNA4LMNA | |
| SCHEMBL25378385 | 0.74 | KMT2A (0.58) | KMT2AALDH1A1CHRNB2CHRNA4LMNA | |
| SCHEMBL7670029 | 0.73 | KMT2A (0.48) | KMT2AKCNA5ALDH1A1MEN1 | |
| SCHEMBL7670432 | 0.73 | NAPRT (0.45) | ALDH1A1CHRNB2CHRNA4LMNA | |
| SCHEMBL7671907 | 0.73 | NAPRT (0.51) | ALDH1A1LMNANAMPT | |
| SCHEMBL27327799 | 0.73 | NAPRT (0.51) | ALDH1A1LMNANAMPT | |
| SCHEMBL2187051 | 0.72 | KDM4E (0.61) | KMT2AALDH1A1CHRNB2CHRNA4LMNA | |
| SCHEMBL7866104 | 0.70 | PKM (0.60) | KMT2AALDH1A1LMNA | |
| SCHEMBL27287575 | 0.70 | CYP1A2 (0.48) | ALDH1A1LMNANAMPT | |
| SCHEMBL6986062 | 0.70 | GAA (0.51) | KMT2AALDH1A1LMNANAMPTGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |