SCHEMBL8067261

SCHEMBL8067261

C=C(C)c1cccc(OCCO)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.49
PRSS1 P07477 9/20 0.47
F2 P00734 1/20 0.44
PLG P00747 1/20 0.44
PRSS2 P07478 1/20 0.44
C1S P09871 1/20 0.44
PRSS3 P35030 1/20 0.44
GAA P10253 1/20 0.44
MAOB P27338 1/20 0.43
SMPD1 P17405 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24749935 0.85 KMT2A (0.47) ALDH1A1KMT2APRSS1F2PLG
SCHEMBL5036731 0.85 KMT2A (0.55) KMT2APRSS1SMPD1
SCHEMBL5033472 0.83 SMPD1 (0.61) KMT2APRSS1SMPD1
SCHEMBL4315663 0.83 MAOB (0.62) ALDH1A1KMT2AMAOB
SCHEMBL25077874 0.82 KMT2A (0.54) ALDH1A1RECQLKMT2A
SCHEMBL16952254 0.81 ALDH1A1 (0.48) ALDH1A1RECQLKMT2APRSS1F2
SCHEMBL7639971 0.79 MAOB (0.43) KMT2APRSS1MAOB
SCHEMBL48418 0.79 ALDH1A1 (0.70) ALDH1A1RECQLKMT2APRSS1GAA
SCHEMBL9375481 0.79 KMT2A (0.49) KMT2APRSS1F2PLGPRSS2
SCHEMBL7457274 0.78 NR1I2 (0.61) ALDH1A1RECQLPRSS1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551867-B1 Laminated transparent plastic material and polymerizable monomer MITSUI CHEMICALS INC (JP) 2000-06-07 EP disclosed
US-5451695-A Acrylic ester monomer with carbamate group, glazing for windows MITSUI TOATSU CHEMICALS, INC. (JP) 1995-09-19 US disclosed
US-5393607-A Glazing materials; hardness, impact strength, scratch resistance MITSUI TOATSU CHEMICLAS, INC. (JP) 1995-02-28 US disclosed
EP-0385457-B1 High surface hardness transparent resin and polymerizable monomer MITSUI TOATSU CHEMICALS (JP) 1994-06-01 EP disclosed
US-5250723-A Copolymerizable monomer containing carbamate or thiocarbamate, ether and isopropenylphenyl groups; protective coatings; optical lenses; hardness; scratch, heat and chemical resistances MITSUI TOATSU CHEMICALS, INC. (JP) 1993-10-05 US disclosed
EP-0551867-A1 Laminated transparent plastic material and polymerizable monomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-21 EP disclosed
US-5145927-A Protective cover for display devices or optical lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
EP-0385457-A2 High surface hardness transparent resin and polymerizable monomer MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-09-05 EP disclosed