Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.46 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067574 | 1.00 | LMNA (0.58) | LMNAGAAKMT2AMEN1CASR | |
| SCHEMBL8068612 | 0.89 | LMNA (0.73) | LMNAGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8068608 | 0.89 | LMNA (0.73) | LMNAGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9127271 | 0.88 | NPSR1 (0.57) | LMNAGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8067516 | 0.88 | LMNA (0.58) | LMNAGAAKMT2AMEN1CASR | |
| SCHEMBL8067520 | 0.88 | LMNA (0.58) | LMNAGAAKMT2AMEN1CASR | |
| SCHEMBL8069626 | 0.87 | LMNA (0.69) | LMNAGAAKMT2AMEN1NLRP3 | |
| SCHEMBL9127545 | 0.87 | LMNA (0.69) | LMNAGAAKMT2AMEN1NLRP3 | |
| SCHEMBL8069628 | 0.87 | LMNA (0.69) | LMNAGAAKMT2AMEN1NLRP3 | |
| SCHEMBL6463046 | 0.87 | LMNA (0.72) | LMNAKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |