Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TCF4 | P15884 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067635 | 0.88 | LMNA (0.58) | TP53LMNAKMT2AMAPTMEN1 | |
| SCHEMBL8067574 | 0.88 | LMNA (0.58) | TP53LMNAKMT2AMAPTMEN1 | |
| SCHEMBL6330701 | 0.87 | TP53 (0.64) | NPSR1TP53LMNASMN1; SMN2CA12 | |
| SCHEMBL6324678 | 0.84 | SMN1; SMN2 (0.60) | NPSR1TP53LMNASMN1; SMN2CA12 | |
| SCHEMBL8068612 | 0.84 | LMNA (0.73) | TP53LMNACA12CA1CA2 | |
| SCHEMBL8068608 | 0.84 | LMNA (0.73) | TP53LMNACA12CA1CA2 | |
| SCHEMBL8067516 | 0.82 | LMNA (0.58) | TP53LMNACA12CA1CA2 | |
| SCHEMBL8067520 | 0.82 | LMNA (0.58) | TP53LMNACA12CA1CA2 | |
| SCHEMBL8069626 | 0.82 | LMNA (0.69) | TP53LMNACA12CA1CA2 | |
| SCHEMBL8069628 | 0.82 | LMNA (0.69) | TP53LMNACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |