Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593707 | 0.79 | NR4A2 (0.41) | NR4A2SOS2MAPTALDH1A1POLB | |
| SCHEMBL5591876 | 0.79 | NR4A2 (0.46) | NR4A2SOS2MAPTALDH1A1POLB | |
| SCHEMBL7456971 | 0.71 | NR4A2 (0.51) | NR4A2SOS2MAPTALDH1A1PDGFRA | |
| Hydrochloric Acid SCHEMBL27295456 | 0.70 | NR4A2 (0.50) | NR4A2SOS2MAPTALDH1A1PDGFRA | |
| SCHEMBL8593709 | 0.70 | NR4A2 (0.41) | NR4A2SOS2MAPTPOLBTHRB | |
| SCHEMBL5591810 | 0.69 | CHKA (0.45) | NR4A2SOS2MAPTALDH1A1POLB | |
| SCHEMBL8067788 | 0.68 | NR4A2 (0.40) | NR4A2SOS2MAPTALDH1A1POLB | |
| SCHEMBL24420728 | 0.67 | NR4A2 (0.58) | NR4A2SOS2MAPTALDH1A1POLB | |
| SCHEMBL21160763 | 0.67 | NR4A2 (0.56) | NR4A2SOS2MAPTALDH1A1CYP1A2 | |
| SCHEMBL9431519 | 0.67 | SLC6A4 (0.48) | NR4A2SOS2MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117884-A | 4-substituted quinoline derivatives having fungicidal activity | DAEUBLE JOHN (US) | 2000-09-12 | — | — | US | claimed |
| EP-0925282-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOWELANCO (US) | 1999-06-30 | — | — | EP | claimed |
| WO-1998005645-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 1998-02-12 | — | — | WO | claimed |