Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591810 | 0.87 | CHKA (0.45) | NR4A2SOS2CYP1A2L3MBTL1SMN1; SMN2 | |
| SCHEMBL8067745 | 0.79 | NR4A2 (0.43) | NR4A2SOS2CYP1A2L3MBTL1LMNA | |
| SCHEMBL11276573 | 0.72 | ALDH1A1 (0.59) | CYP1A2L3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8593707 | 0.70 | NR4A2 (0.41) | NR4A2SOS2CYP1A2ALDH1A1MAPT | |
| SCHEMBL24420728 | 0.70 | NR4A2 (0.58) | NR4A2SOS2CYP1A2L3MBTL1LMNA | |
| SCHEMBL21160763 | 0.70 | NR4A2 (0.56) | NR4A2SOS2CYP1A2L3MBTL1LMNA | |
| SCHEMBL9431519 | 0.69 | SLC6A4 (0.48) | NR4A2SOS2CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL11817575 | 0.69 | NCF1 (0.41) | CYP1A2L3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4509324 | 0.69 | TLR8 (0.59) | NR4A2SOS2CYP1A2MAPTKMT2A | |
| SCHEMBL5654973 | 0.68 | ALDH1A1 (0.53) | L3MBTL1LMNASMN1; SMN2ALDH1A1ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |