Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068855 | 0.79 | KDM4E (0.59) | SMN1; SMN2ADRB2GAA | |
| SCHEMBL8068245 | 0.77 | SLC7A5 (0.47) | MAPTEPHX2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL28519071 | 0.76 | CYP3A4 (0.57) | ALDH1A1CYP4F2CYP4A11SMN1; SMN2CYP3A4 | |
| SCHEMBL28519068 | 0.76 | CYP3A4 (0.57) | ALDH1A1CYP4F2CYP4A11SMN1; SMN2CYP3A4 | |
| Phenylethyl Alcohol SCHEMBL12501711 | 0.76 | CYP4F2 (0.63) | MAPTALDH1A1L3MBTL1MAPK1CYP4F2 | |
| SCHEMBL112999 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL1332625 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| Benzene SCHEMBL28160801 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL1873977 | 0.76 | ALDH1A1 (0.68) | MAPTALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL25267822 | 0.75 | NPSR1 (0.48) | SMN1; SMN2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028080-A | Quinolin-2-(1H)-ones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-02-22 | — | — | US | disclosed |