Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16926996 | 0.97 | TSHR (0.44) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL5067840 | 0.97 | TSHR (0.44) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL28287650 | 0.97 | TSHR (0.44) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL5819405 | 0.94 | OPRM1 (0.48) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL263101 | 0.91 | — | — | |
| SCHEMBL11327130 | 0.91 | TSHR (0.50) | OPRM1LMNADNM1TSHRTHRB | |
| Ether SCHEMBL17045842 | 0.86 | OPRM1 (0.39) | OPRM1LMNADNM1TSHRTHRB | |
| SCHEMBL2218808 | 0.84 | — | — | |
| SCHEMBL2178897 | 0.82 | — | — | |
| SCHEMBL135671 | 0.81 | LMNA (0.41) | OPRM1LMNADNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143826-A | METHYL METHACRYLATE POLYMER; BLOCK POLYMER OF AROMATIC VINYL COMPOUND AND/OR METHACRYLATE ESTER; SOFTNESS, TRANSPARENCY | KURARAY CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0832929-B1 | Polymer blend | KURARAY CO (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0832929-A1 | Polymer blend | KURARAY CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |