Phthalic Acid

Phthalic Acid

SCHEMBL8067893

CC1(C)CCCC(C)(C)N1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.52
ALDH1A1 P00352 4/20 0.52
AKR1C3 P42330 2/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
GAA P10253 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
HMGB1 P09429 1/20 0.41
HPGD P15428 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL6544237 1.00 ALOX15 (0.52) ALOX15ALDH1A1AKR1C3KMT2AMEN1
Benzoic Acid SCHEMBL23581094 0.85 TSHR (0.52) ALOX15KMT2AMEN1GAACYP3A4
Terephthalic Acid SCHEMBL6544696 0.81 TP53 (0.48) ALDH1A1CYP3A4CA12CA1CA2
Isophthalic Acid SCHEMBL6544630 0.79 CA12 (0.44) ALDH1A1KMT2AMEN1GAACYP2C9
Phthalic Acid SCHEMBL11485468 0.79 ALOX15 (0.61) ALOX15ALDH1A1KMT2AMEN1GAA
SCHEMBL21891706 0.77 ALDH1A1 (0.47) ALOX15ALDH1A1AKR1C3KMT2AMEN1
Phthalic Acid SCHEMBL11171682 0.77 ALDH1A1 (0.56) ALOX15ALDH1A1AKR1C3CYP3A4CYP2D6
Acetic Acid SCHEMBL986871 0.75 FFAR3 (0.38) ALDH1A1KMT2AMEN1GAACYP2C19
Phthalic Acid SCHEMBL590260 0.75 ALDH1A1 (0.74) ALOX15ALDH1A1AKR1C3KMT2ACYP3A4
Phthalic Acid SCHEMBL2160580 0.75 ALDH1A1 (0.82) ALOX15ALDH1A1AKR1C3GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6121393-A USING A CATALYST OF A SOLID TITANIUM CATALYST COMPONENT CONTAINING MAGNESIUM, TITANIUM AND HALOGEN ATOMS, AN ORGANO-ALUMINUM COMPOUND, AND A BRANCHED CHAIN ALKYL CHLORIDE OR TITANIUM TETRACHLORIDE; STEREOSPECIFIC; POLYPROPYLENE MITSUI CHEMICALS (JP) 2000-09-19 US disclosed