SCHEMBL8068048

SCHEMBL8068048

OCCOc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
LMNA P02545 3/20 0.44
HTT P42858 2/20 0.44
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.40
AR P10275 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
IDO1 P14902 1/20 0.39
ALDH1A1 P00352 1/20 0.39
RECQL P46063 1/20 0.39
TIPARP Q7Z3E1 2/20 0.39
HTR7 P34969 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR2B P41595 1/20 0.38
PDE5A O76074 1/20 0.38
DRD2 P14416 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21380737 0.92 LMNA (0.47) PNMTLMNAHTTRAB9ANPC1
SCHEMBL30352842 0.92 LMNA (0.47) PNMTLMNAHTTRAB9ANPC1
SCHEMBL28443529 0.88 IDO1 (0.49) PNMTLMNAHTTRAB9ANPC1
Methacrylic Acid SCHEMBL29066041 0.87 NPC1 (0.44) LMNAHTTRAB9ANPC1MEN1
SCHEMBL5749931 0.84 PNMT (0.54) PNMTLMNARAB9ANPC1TP53
SCHEMBL28716199 0.84 ESR1 (0.40) PNMTLMNAHTTARIDO1
SCHEMBL28306313 0.84 LMNA (0.43) PNMTLMNAHTTRAB9AMEN1
SCHEMBL21360083 0.84 IDO1 (0.51) PNMTLMNAHTTRAB9ANPC1
SCHEMBL28607402 0.83 LMNA (0.53) PNMTLMNARAB9ANPC1HTR7
SCHEMBL29812530 0.83 PNMT (0.40) PNMTLMNAHTTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480385-B Method for preparing polycarbonate by using binuclear ionic liquid as catalyst 中国科学院过程工程研究所 2021-11-30 CN claimed
CN-112480385-A Method for preparing polycarbonate by using binuclear ionic liquid as catalyst 中国科学院过程工程研究所 2021-03-12 CN claimed
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US claimed
CN-114787116-A Compound, resin, polycarbonate resin, and optical molded body 三井化学株式会社 2022-07-22 CN disclosed
CN-112480385-B Method for preparing polycarbonate by using binuclear ionic liquid as catalyst 中国科学院过程工程研究所 2021-11-30 CN disclosed
CN-112480385-A Method for preparing polycarbonate by using binuclear ionic liquid as catalyst 中国科学院过程工程研究所 2021-03-12 CN disclosed
EP-0761604-B1 An agent for water treatment NIPPON CATALYTIC CHEM IND (JP) 2000-06-14 EP disclosed
US-5948268-A DISSOLVING IN WATER TO BE TREATED A POLYMER FORMED FROM WATER SOLUBLE MONOMER UNITS COMPRISING A (POLY)ALKYLENE OXIDE END CAPPED WITH AN ADDITION POLYMERIZABLE GROUP AT ONE END AND AN INTENSELY FLUORESCENT GROUP AT OTHER NIPPON SHOKUBAI CO., LTD. (JP) 1999-09-07 US disclosed
EP-0761604-A2 An agent for water treatment NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-12 EP disclosed