Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000114 | 0.81 | MCL1 (0.57) | RAB9ANR3C1MCL1ALDH1A1MAPT | |
| SCHEMBL7065889 | 0.75 | KDM4E (0.77) | RAB9AALDH1A1MAPTHTTLMNA | |
| SCHEMBL2372705 | 0.72 | MCL1 (0.62) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL16832165 | 0.72 | RAB9A (0.67) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL16832167 | 0.72 | RAB9A (0.67) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL28582158 | 0.71 | GAA (0.57) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL3134184 | 0.71 | NR3C1 (1.00) | NR3C1NR3C2 | |
| SCHEMBL11512517 | 0.71 | MCL1 (0.61) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL11512510 | 0.71 | MCL1 (0.61) | RAB9AMCL1ALDH1A1MAPTHTT | |
| SCHEMBL9577232 | 0.71 | GAA (0.69) | RAB9AMCL1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |