Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693477 | 0.88 | HTT (0.58) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL14691256 | 0.86 | MAPT (0.50) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL14691259 | 0.86 | MAPT (0.50) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL14706208 | 0.85 | ALDH1A1 (0.52) | HTTSMN1; SMN2MAPTMAPK1ALDH1A1 | |
| SCHEMBL11526803 | 0.82 | HTT (0.71) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL28762600 | 0.82 | HTT (0.56) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL8067374 | 0.81 | ALDH1A1 (0.45) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL7816540 | 0.81 | MAPT (0.58) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL2935107 | 0.81 | HTT (0.69) | HTTSMN1; SMN2MAPTMAPK1TDP1 | |
| SCHEMBL7600834 | 0.80 | ALDH1A1 (0.72) | HTTSMN1; SMN2MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |