Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220355 | 0.81 | BIRC3 (0.37) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL8056824 | 0.78 | ADRB3 (0.30) | — | |
| SCHEMBL8224732 | 0.73 | XIAP (0.33) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL8293914 | 0.69 | ADRB3 (0.45) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL13896390 | 0.69 | ADRB3 (0.44) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL13962141 | 0.68 | ADRB3 (0.39) | XIAPBIRC3BIRC2 | |
| SCHEMBL1655875 | 0.68 | BIRC3 (0.38) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL8003495 | 0.67 | XIAP (0.32) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL8129662 | 0.67 | ADRB3 (0.43) | XIAPBIRC3BIRC2HDAC4HDAC1 | |
| SCHEMBL12785318 | 0.66 | ADRB3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |