Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.33 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | TERF2 | Q15554 | 4/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.32 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220355 | 0.84 | BIRC3 (0.37) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL8068142 | 0.73 | XIAP (0.33) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL12820226 | 0.72 | XIAP (0.35) | XIAPBIRC3BIRC2NTSR1HDAC1 | |
| SCHEMBL1655875 | 0.71 | BIRC3 (0.38) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL8293914 | 0.69 | ADRB3 (0.45) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL8003495 | 0.69 | XIAP (0.32) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL13962141 | 0.68 | ADRB3 (0.39) | XIAPBIRC3BIRC2 | |
| SCHEMBL1645089 | 0.68 | F2 (0.37) | XIAPBIRC3BIRC2HDAC1HDAC4 | |
| SCHEMBL13961573 | 0.67 | ADRB3 (0.37) | XIAPBIRC3BIRC2 | |
| SCHEMBL8249384 | 0.66 | F2 (0.37) | XIAPBIRC3BIRC2HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021956-A2 | ACYLAMINOHETEROARYL HEPATITIS C VIRUS PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |