SCHEMBL8068162

SCHEMBL8068162

CCCCCCCCc1cc(CN2C(=O)C3=C(CCCC3)C2=O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
S1PR4 O95977 1/20 0.34
S1PR5 Q9H228 1/20 0.34
RORA P35398 1/20 0.34
RORC P51449 1/20 0.34
RORB Q92753 1/20 0.34
POLB P06746 1/20 0.33
AGTR1 P30556 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28879537 0.85 LMNA (0.38) KDM4ELMNAMEN1KMT2AALDH1A1
SCHEMBL9437946 0.85 TSHR (0.40) MEN1KMT2AALDH1A1HPGDNPC1
SCHEMBL8588340 0.83 CNR1 (0.35) KDM4ELMNANPC1RAB9APOLB
SCHEMBL456993 0.83 NPC1 (0.42) KDM4ELMNAALDH1A1HPGDNPC1
SCHEMBL31267544 0.83 NPC1 (0.42) KDM4ELMNAALDH1A1HPGDNPC1
SCHEMBL30298106 0.83 NPC1 (0.42) KDM4ELMNAALDH1A1HPGDNPC1
SCHEMBL29353331 0.83 NPC1 (0.49) KDM4ELMNAALDH1A1CYP1A2CYP2C9
SCHEMBL272931 0.83 NPC1 (0.49) KDM4ELMNAALDH1A1CYP1A2CYP2C9
SCHEMBL23222483 0.82 LMNA (0.39) KDM4ELMNAALDH1A1CYP1A2CYP2C9
SCHEMBL11088731 0.82 NPC1 (0.43) KDM4ELMNAALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100199491-A1 MANUFACTURING METHOD OF IMAGE PICK-UP DEVICE, IMAGE PICK-UP DEVICE AND OPTICAL ELEMENT KONICA MINOLTA OPTO, INC. (JP) 2010-08-12 US disclosed
JP-2000336178-A BASE FILM FOR DECORATION SHEET OKURA IND CO LTD 2000-12-05 JP disclosed
JP-2000313813-A RESIN COMPOSITION FOR IRRADIATION WITH RADIATION OKURA IND CO LTD 2000-11-14 JP disclosed