Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066630 | 1.00 | GPR119 (0.49) | GPR119KCNH2GPR183HRH2HRH1 | |
| SCHEMBL2895122 | 0.91 | GPR119 (0.47) | GPR119KCNH2GPR183 | |
| SCHEMBL3651584 | 0.91 | GPR119 (0.47) | GPR119KCNH2GPR183 | |
| SCHEMBL2900087 | 0.91 | GPR119 (0.47) | GPR119KCNH2GPR183 | |
| SCHEMBL2895119 | 0.91 | GPR119 (0.47) | GPR119KCNH2GPR183 | |
| SCHEMBL2897711 | 0.89 | GPR119 (0.52) | GPR119KCNH2GPR183HRH2HRH1 | |
| SCHEMBL8071988 | 0.88 | GPR119 (0.41) | GPR119KCNH2GPR183HRH2HRH1 | |
| SCHEMBL13067892 | 0.88 | GPR119 (0.49) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL8071087 | 0.88 | GPR119 (0.49) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL8066261 | 0.86 | GPR119 (0.44) | GPR119KCNH2GPR183HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |