Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588945 | 0.83 | ACHE (0.45) | BRD4CREBBPALDH1A1HPGDMAOA | |
| SCHEMBL6594253 | 0.79 | ALDH1A1 (0.43) | BRD4CREBBPALDH1A1HPGDHCAR2 | |
| SCHEMBL6591994 | 0.76 | ACHE (0.48) | MAOAPRKDCACHEMAOB | |
| SCHEMBL17544040 | 0.74 | MEN1 (0.51) | ALDH1A1HPGDPRKDCMAOBLMNA | |
| SCHEMBL30402977 | 0.74 | MEN1 (0.51) | ALDH1A1HPGDPRKDCMAOBLMNA | |
| SCHEMBL6590245 | 0.73 | ACHE (0.43) | MAOAACHEMAOB | |
| SCHEMBL6597434 | 0.72 | ACHE (0.44) | MAOAACHEMAOB | |
| SCHEMBL30402532 | 0.71 | ALK (0.42) | ALDH1A1HPGDMAOADYRK1APRKDC | |
| SCHEMBL6593862 | 0.71 | MAOB (0.44) | MAOAACHEMAOB | |
| SCHEMBL17544806 | 0.71 | ALK (0.42) | ALDH1A1HPGDMAOADYRK1APRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000128878-A | BENZOFURYL-ALPHA-PYRIDONE DERIVATIVE | TEIJIN LTD | 2000-05-09 | — | — | JP | disclosed |