Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464649 | 0.84 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL7878967 | 0.81 | PTGS2 (0.61) | PTGS2PTGS1ALDH1A1ABCB11TUBB4A | |
| SCHEMBL8989537 | 0.74 | PTGS2 (0.67) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL6728766 | 0.74 | PTGS2 (0.55) | PTGS2PTGS1ALDH1A1ABCB11MAPT | |
| SCHEMBL6737152 | 0.73 | PTGS2 (0.62) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL7867755 | 0.73 | PTGS2 (0.73) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL8199019 | 0.71 | PTGS2 (0.62) | PTGS2PTGS1ALDH1A1ABCB11TUBB4A | |
| SCHEMBL6729441 | 0.71 | PTGS2 (0.62) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL6738596 | 0.71 | PTGS2 (0.69) | PTGS2PTGS1ALDH1A1ABCB11 | |
| SCHEMBL6823755 | 0.70 | PTGS2 (0.66) | PTGS2PTGS1ALDH1A1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |