Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700867 | 1.00 | NMBR (0.58) | NMBRMAPTHTTGAACASP1 | |
| SCHEMBL8706625 | 0.84 | NMBR (0.49) | NMBRMAPTHTTGAACASP1 | |
| SCHEMBL5913306 | 0.82 | CTSL (0.53) | MAPTTACR1SSTR1SMN1; SMN2 | |
| SCHEMBL8528011 | 0.82 | CTSL (0.53) | MAPTTACR1SSTR1SMN1; SMN2 | |
| SCHEMBL27621167 | 0.82 | CTSL (0.53) | MAPTTACR1SSTR1SMN1; SMN2 | |
| SCHEMBL8022191 | 0.82 | CTSL (0.53) | MAPTTACR1SSTR1SMN1; SMN2 | |
| SCHEMBL31000751 | 0.81 | MDM4 (0.46) | — | |
| SCHEMBL31000753 | 0.81 | MDM4 (0.46) | — | |
| SCHEMBL6480706 | 0.81 | MDM4 (0.46) | — | |
| SCHEMBL6481998 | 0.81 | MDM4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030983-A | ANTITUMOR AND -CARCINOGENIC AGENTS; ANTIBIOTICS; BACTERICIDES; VIRICIDES; PARACITICIDES; ENZYME INHIBITORS; POLYMERASES; FARNESYL-PROTEIN TRANSFERASE; RAS PROTEINS | BALL STATE UNIVERSITY (US) | 2000-02-29 | — | — | US | disclosed |
| US-6025372-A | Somatostatin agonists | MERCK & CO., INC. (US) | 2000-02-15 | — | — | US | disclosed |
| US-5712289-A | ANTITUMOR AGENTS, INTERMEDIATES FOR LAVENDAMYCINS | BALL STATE UNIVERSITY (US) | 1998-01-27 | — | — | US | disclosed |
| US-5646150-A | ADMINISTERING AS ANTITUMOR AGENT, ANTIPROTOZOA AGENT, VIRICIDE, PARASITICIDE, OR BACTERICIDE | BALL STATE UNIVERSITY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5525611-A | ANTITUMOR AGENT, BACTERICIDES, VIRICIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1996-06-11 | — | — | US | disclosed |
| WO-1994029308-A1 | LAVENDAMYCIN ANALOGS, THEIR USE AND PREPARATION | BEHFOROUZ MOHAMMAD (US) | 1994-12-22 | — | — | WO | disclosed |