Phenethylamine

Phenethylamine

SCHEMBL8068653

C=CCNCc1ccccc1.NCCc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.55
CYP2A6 P11509 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
LOXL2 Q9Y4K0 1/20 0.55
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
SIGMAR1 Q99720 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
DPP7 Q9UHL4 1/20 0.44
MAOA P21397 2/20 0.41
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH7 P40394 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL681149 0.87 MEN1 (0.56) SMN1; SMN2MAPTGAASIGMAR1MEN1
Ammonia Solution, Strong SCHEMBL27753398 0.85 MEN1 (0.54) SMN1; SMN2MAPTGAASIGMAR1MEN1
Bromide SCHEMBL9394202 0.85 MEN1 (0.54) SMN1; SMN2MAPTGAASIGMAR1MEN1
Water SCHEMBL3478298 0.85 MEN1 (0.54) SMN1; SMN2MAPTGAASIGMAR1MEN1
Hydrochloric Acid SCHEMBL250190 0.85 MEN1 (0.54) SMN1; SMN2MAPTGAASIGMAR1MEN1
Phenethylamine SCHEMBL5746322 0.83 HTR2A (0.73) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Hypochlorous Acid SCHEMBL28117107 0.80 MEN1 (0.48) SMN1; SMN2MAPTGAAMEN1KMT2A
Phenethylamine SCHEMBL11698137 0.79 HTR2A (0.73) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenol SCHEMBL28870632 0.79 MEN1 (0.47) MAPTGAAMEN1KMT2ATDP1
Oxalic Acid SCHEMBL29028526 0.79 KDM4E (0.57) MAPTGAAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046326-A REACTING ETHYLENE CARBONATE AND ISOCYANURIC ACID USING HETEROCYCLIC AMINE CATALYST ESSEX GROUP (US) 2000-04-04 US disclosed