Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428431 | 0.81 | PTPN1 (0.37) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL8205778 | 0.76 | PTPN1 (0.40) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL21996373 | 0.75 | PTPN1 (0.39) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL10519826 | 0.71 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL8477691 | 0.71 | KDM4E (0.31) | L3MBTL1 | |
| SCHEMBL10572506 | 0.70 | PTPN1 (0.40) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL9730908 | 0.68 | — | — | |
| SCHEMBL10519639 | 0.67 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL17923128 | 0.67 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ACP1CDC25B | |
| SCHEMBL8306149 | 0.67 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ACP1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| US-5981558-A | ANTIMICROBIAL ACTIVITY AND ANTITUMOR ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0918058-A1 | DC 107 DERIVATIVES (1) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |