Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068906 | 0.81 | PTPN1 (0.34) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL8205778 | 0.78 | PTPN1 (0.40) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL21996373 | 0.76 | PTPN1 (0.39) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL30457001 | 0.72 | ALDH1A1 (0.38) | PTPN1ACP1CDC25BHSD17B10ALDH1A1 | |
| SCHEMBL10572506 | 0.72 | PTPN1 (0.40) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL3937204 | 0.71 | PTGS2 (0.32) | — | |
| SCHEMBL16148400 | 0.70 | PTPN1 (0.37) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL9730908 | 0.69 | — | — | |
| SCHEMBL10519826 | 0.68 | PTPN1 (0.38) | PTPN1ACP1CDC25BLMNAHSD17B10 | |
| SCHEMBL10519639 | 0.68 | PTPN1 (0.38) | PTPN1ACP1CDC25BLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |
| EP-0638563-B1 | Aminoaryl-1,3-oxazin-2,4-diones | BAYER AG (DE) | 1997-10-15 | — | — | EP | disclosed |
| US-5593944-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-14 | — | — | US | disclosed |
| EP-0638563-A1 | Aminoaryl-1,3-oxazin-2,4-diones | BAYER AG (DE) | 1995-02-15 | — | — | EP | disclosed |