Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572506 | 0.75 | PTPN1 (0.40) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL18957266 | 0.74 | — | — | |
| SCHEMBL9730908 | 0.73 | — | — | |
| SCHEMBL10519826 | 0.71 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL17923128 | 0.71 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL10519639 | 0.71 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL18098832 | 0.70 | ALDH1A1 (0.44) | PTPN1ALDH1A1CRHBPCRHR2RAB9A | |
| SCHEMBL7428431 | 0.68 | PTPN1 (0.37) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL17961040 | 0.67 | PTPN1 (0.38) | PTPN1LMNAHSD17B10ALDH1A1HTT | |
| SCHEMBL8068906 | 0.67 | PTPN1 (0.34) | PTPN1LMNAHSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250268257-A1 | HERBICIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2025-08-28 | — | — | US | disclosed |
| EP-4255889-A1 | HERBICIDAL DERIVATIVES | Syngenta Crop Protection AG (CH) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117445-A1 | HERBICIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022117445-A1 | HERBICIDAL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-06-09 | — | — | WO | disclosed |
| US-20200325140-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | AKARNA THERAPEUTICS, LTD. (CH) | 2020-10-15 | — | — | US | disclosed |
| WO-2020063663-A1 | TRICYCLIC ANALOG, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院上海药物研究所 | 2020-04-02 | — | — | WO | disclosed |
| EP-3162805-B1 | NOVEL PHARMACEUTICAL COMPOUND HAVING A CHOLESTEROL ACYLTRANSFERASE ISOZYME 2 (ACAT2) -INHIBITING ACTIVITY | SCHOOL JURIDICAL PERSON KITASATO INST (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-10278962-B2 | Tricyclic analogues, preparation method and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2019-05-07 | — | — | US | disclosed |
| US-20180064696-A1 | TRICYCLIC ANALOGUES, PREPARATION METHOD AND USES THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2018-03-08 | — | — | US | disclosed |
| US-20180064696-A1 | TRICYCLIC ANALOGUES, PREPARATION METHOD AND USES THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2018-03-08 | — | — | US | disclosed |
| US-9896456-B2 | Pharmaceutical compound having inhibitory activity against cholesterol acyltransferase isozyme 2 (ACAT2) | SCHOOL JURIDICAL PERSON KITASATO INSTITUTE (JP) | 2018-02-20 | — | — | US | disclosed |
| EP-3272755-A1 | CLASS OF TRICYCLIC ANALOGUE, PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-01-24 | — | — | EP | disclosed |
| WO-2017205633-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | AKARNA THERAPEUTICS, LTD. (GB) | 2017-11-30 | — | — | WO | disclosed |
| US-9738634-B2 | Heterocyclic amide compound and herbicide | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-22 | — | — | US | disclosed |
| US-20170204114-A1 | NOVEL PHARMACEUTICAL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST CHOLESTEROL ACYLTRANSFERASE ISOZYME 2 (ACAT2) | SCHOOL JURIDICAL PERSON KITASATO INSTITUTE (JP) | 2017-07-20 | — | — | US | disclosed |
| EP-3162805-A1 | NOVEL PHARMACEUTICAL COMPOUND HAVING A CHOLESTEROL ACYLTRANSFERASE ISOZYME 2 (ACAT2) -INHIBITING ACTIVITY | School Juridical Person Kitasato Institute (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-20160221998-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| EP-3045455-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | Syngenta Participations AG (CH) | 2016-07-20 | — | — | EP | disclosed |
| EP-0900216-A1 | 1,3-OXAZIN-4-ONE DERIVATES AS HERBICIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040041-A1 | 1,3-OXAZIN-4-ONE DERIVATES AS HERBICIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325140-A1 | FUSED BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASE | VHL, BRDT, PAICS | PTPN1 4800/4885LMNA 450/4885HSD17B10 276/4885 |
| US-20180064696-A1 | TRICYCLIC ANALOGUES, PREPARATION METHOD AND USES THEREOF | ACAT2, ACAT1, LCAT | PTPN1 3226/4885LMNA 2140/4885HSD17B10 54/4885 |
| US-20250268257-A1 | HERBICIDAL DERIVATIVES | DDT, CYP1B1, CYP1A1 | PTPN1 740/4885LMNA 3950/4885HSD17B10 124/4885 |
| US-10278962-B2 | Tricyclic analogues, preparation method and uses thereof | ACAT2, ACAT1, LCAT | PTPN1 3230/4885LMNA 2102/4885HSD17B10 53/4885 |
| US-20160221998-A1 | HETEROCYCLIC AMIDE COMPOUND AND HERBICIDE | GLRA1, RER1, H1-4 | PTPN1 1745/4885LMNA 4561/4885HSD17B10 1506/4885 |
| US-20170204114-A1 | NOVEL PHARMACEUTICAL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST CHOLESTEROL ACYLTRANSFERASE ISOZYME 2 (ACAT2) | ACAT2, LCAT, ACAT1 | PTPN1 544/4885LMNA 4370/4885HSD17B10 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.