Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 3/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070787 | 0.84 | NPC1 (0.48) | BRS3OPRL1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8061857 | 0.84 | OPRL1 (0.60) | BRS3OPRL1KDM4EALDH1A1SMN1; SMN2 | |
| Ufiprazole SCHEMBL662986 | 0.81 | BRS3 (0.84) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ufiprazole SCHEMBL29455226 | 0.81 | BRS3 (0.84) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7851296 | 0.81 | BRS3 (0.69) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ufiprazole SCHEMBL7950477 | 0.81 | BRS3 (0.82) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ufiprazole SCHEMBL7929368 | 0.81 | BRS3 (0.82) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ufiprazole SCHEMBL31529606 | 0.81 | BRS3 (0.82) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8070889 | 0.80 | KMT2A (0.42) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ufiprazole SCHEMBL3180530 | 0.79 | BRS3 (0.76) | BRS3KDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | claimed |
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |