Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MYOC | Q99972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069365 | 1.00 | MEN1 (0.55) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL8070027 | 0.81 | ABCG2 (0.60) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL8070029 | 0.81 | ABCG2 (0.60) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL8058439 | 0.81 | CNR1 (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL8067595 | 0.81 | CNR1 (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL8058435 | 0.81 | CNR1 (0.58) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL3461321 | 0.80 | HSD17B10 (0.70) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL10577831 | 0.80 | HSD17B10 (0.70) | MEN1KMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL8058297 | 0.78 | FPR2 (0.55) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8067558 | 0.78 | FPR2 (0.55) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |