Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MYOC | Q99972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070027 | 1.00 | ABCG2 (0.60) | ABCG2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8074018 | 0.85 | FPR2 (0.57) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8072202 | 0.85 | FPR2 (0.57) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8074023 | 0.85 | FPR2 (0.57) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8067629 | 0.84 | FPR2 (0.56) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8067627 | 0.84 | FPR2 (0.56) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL6301913 | 0.83 | MEN1 (0.74) | ABCG2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8073834 | 0.83 | RAB9A (0.62) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8067530 | 0.83 | UTS2R (0.57) | MEN1KMT2ANPC1RAB9AFPR2 | |
| SCHEMBL8073835 | 0.83 | RAB9A (0.62) | MEN1KMT2ANPC1RAB9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994006757-A1 | AGENTS ACTING AT CHOLECYSTOKININ RECEPTORS | WARNER-LAMBERT COMPANY (US) | 1994-03-31 | — | — | WO | disclosed |