Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148833 | 0.89 | PLAU (0.43) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL27944193 | 0.82 | L3MBTL1 (0.50) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL1727266 | 0.82 | SRC (0.52) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL27537974 | 0.81 | POLB (0.50) | SRCCYP1A2GAACYP2C9PKM | |
| SCHEMBL16409699 | 0.78 | ANPEP (0.43) | SRCELANECYP1A2GAACYP2C9 | |
| SCHEMBL11281739 | 0.74 | SRC (0.54) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL29012567 | 0.74 | SRC (0.48) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL5958828 | 0.72 | SRC (0.50) | SRCELANEANPEPLAP3KMT2A | |
| SCHEMBL14390657 | 0.72 | ALDH1A1 (0.42) | SRCELANECYP1A2GAACYP2C9 | |
| SCHEMBL12330526 | 0.72 | ALDH1A1 (0.45) | SRCELANECYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037038-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-22 | — | — | WO | disclosed |