Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069608 | 1.00 | RAB9A (0.72) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8058760 | 0.87 | EPHX1 (0.67) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8058763 | 0.87 | EPHX1 (0.67) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL12196175 | 0.84 | RAB9A (1.00) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8058343 | 0.84 | RAB9A (0.73) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8058342 | 0.84 | RAB9A (0.73) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL2751657 | 0.83 | RAB9A (0.97) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8067568 | 0.83 | EPHX1 (0.73) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8067991 | 0.81 | RAB9A (0.72) | RAB9ANPC1EPHX1MEN1KMT2A | |
| SCHEMBL8067993 | 0.81 | RAB9A (0.72) | RAB9ANPC1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103761-A | Agents acting at cholecystokinin receptors | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| US-5389682-A | Appetite suppressants, anxiolytic agents, gastric acid inhibition | WARNER-LAMBERT COMPANY (US) | 1995-02-14 | — | — | US | disclosed |