Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312762 | 0.86 | SRC (0.64) | SRCCES2CES1CYP2D6HPGD | |
| SCHEMBL8506407 | 0.85 | ALDH1A1 (0.48) | HPGDLMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL15455826 | 0.84 | SRC (0.61) | SRCCES2CES1CYP2D6HPGD | |
| SCHEMBL11012611 | 0.84 | SRC (0.61) | SRCCES2CES1CYP2D6HPGD | |
| SCHEMBL21694423 | 0.82 | SRC (0.73) | SRCCES2CES1CYP2D6LMNA | |
| SCHEMBL7303581 | 0.82 | SRC (0.73) | SRCCES2CES1CYP2D6HPGD | |
| SCHEMBL3678814 | 0.82 | SRC (0.73) | SRCCES2CES1CYP2D6HPGD | |
| SCHEMBL9374736 | 0.80 | SRC (0.56) | SRCCYP2D6HPGDLMNAMAPK1 | |
| SCHEMBL27894375 | 0.80 | ACP3 (0.45) | HPGDLMNAMAPK1KMT2AALDH1A1 | |
| SCHEMBL2171712 | 0.79 | ALDH1A1 (0.45) | SRCHPGDLMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620857-B1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LTD (GB) | 2000-08-02 | — | — | EP | disclosed |
| US-5686275-A | LACTATE DEHYDROGENASE | GENZYME LTD. (GB) | 1997-11-11 | — | — | US | disclosed |
| US-5571654-A | Toner compositions with negative charge enhancing additives | XEROX CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| US-5538829-A | Toner compositions with zinc and boron charge enhancing additives | XEROX CORPORATION (US) | 1996-07-23 | — | — | US | disclosed |
| US-5532098-A | Toner compositions with negative charge enhancing additives | XEROX CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5409794-A | Toner compositions with metal chelate charge enhancing additives | XEROX CORPORATION (US) | 1995-04-25 | — | — | US | disclosed |
| EP-0620857-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | Genzyme Limited (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013215-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LIMITED (GB) | 1993-07-08 | — | — | WO | disclosed |