Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 6/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069462 | 0.90 | LMNA (0.35) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8079114 | 0.88 | LMNA (0.36) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8079094 | 0.88 | LMNA (0.37) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8069715 | 0.88 | LMNA (0.40) | RAB9ALMNASMN1; SMN2GALR3NR2F2 | |
| SCHEMBL8079245 | 0.88 | LMNA (0.50) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8079105 | 0.88 | LMNA (0.40) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8079200 | 0.86 | LMNA (0.40) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8079174 | 0.86 | LMNA (0.37) | RAB9ALMNASMN1; SMN2GALR3NR2F2 | |
| SCHEMBL8079086 | 0.86 | RAB9A (0.36) | CACNA1GCACNA1HCACNA1IRAB9ALMNA | |
| SCHEMBL8077532 | 0.86 | LMNA (0.41) | RAB9ALMNASMN1; SMN2GALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |