⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894086 | 0.82 | — | — | |
| SCHEMBL12873374 | 0.80 | LPAR3 (0.40) | — | |
| SCHEMBL11598870 | 0.80 | TSHR (0.42) | — | |
| SCHEMBL11793622 | 0.80 | ACHE (0.39) | — | |
| SCHEMBL12876257 | 0.78 | TSHR (0.40) | — | |
| Hydrochloric Acid SCHEMBL11048279 | 0.78 | TSHR (0.40) | — | |
| SCHEMBL10758272 | 0.77 | — | — | |
| SCHEMBL17211914 | 0.77 | LPAR3 (0.41) | — | |
| SCHEMBL11649582 | 0.77 | LAP3 (0.46) | — | |
| SCHEMBL12146353 | 0.77 | LAP3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725071-B1 | Process for preparing alkaline metal salts of phosphonic acids mono methyl esters | TICONA GMBH (DE) | 2000-07-19 | — | — | EP | claimed |
| US-5705670-A | Process for the preparation of alkali metal salts of phosphonic acid monomethyl esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | claimed |
| CN-115109086-A | Process for preparing alkyl phosphonates | 利尔化学股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-20170260219-A1 | PHOSPHONATE COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| US-9663543-B2 | Phosphonate compounds for treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160362432-A1 | PHOSPHONATE COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2016-12-15 | — | — | US | disclosed |
| US-20150239921-A1 | Phosphonate Compounds for Treatment of Complement Mediated Disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | US | disclosed |
| US-5705670-A | Process for the preparation of alkali metal salts of phosphonic acid monomethyl esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |