Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.56 |
| ▸ | CCR2 | P41597 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924383 | 0.85 | CCR2 (0.76) | PTGS2CCR2TBXA2R | |
| SCHEMBL2927892 | 0.84 | PTGS2 (0.61) | PTGS2CCR2PTGS1LMNATBXA2R | |
| SCHEMBL2929297 | 0.82 | PTGS2 (0.82) | PTGS2CCR2LMNAALDH1A1HTT | |
| SCHEMBL2929127 | 0.77 | PTGS2 (0.56) | PTGS2CCR2PTGS1TBXA2R | |
| SCHEMBL2924747 | 0.75 | PTGS2 (0.52) | PTGS2CCR2PTGS1TBXA2R | |
| SCHEMBL2928445 | 0.75 | PTGS2 (0.52) | PTGS2CCR2PTGS1TSHRALDH1A1 | |
| SCHEMBL2923938 | 0.74 | PTGS2 (0.56) | PTGS2CCR2PTGS1LMNATBXA2R | |
| SCHEMBL16211084 | 0.74 | CCR2 (0.81) | PTGS2CCR2 | |
| SCHEMBL2929234 | 0.73 | PTGS2 (0.55) | PTGS2CCR2PTGS1ALDH1A1TBXA2R | |
| SCHEMBL4366544 | 0.73 | CCR2 (0.71) | PTGS2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000136182-A | INDOLE DERIVATIVE AND MONO- OR DI-AZIDOINDOLE DERIVATIVE HAVING AMINO BAND | CHUGAI PHARMACEUT CO LTD | 2000-05-16 | — | — | JP | disclosed |