Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ENO1 | P06733 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Foscarnet SCHEMBL23633 | 0.82 | — | — | |
| SCHEMBL215192 | 0.82 | — | — | |
| Foscarnet SCHEMBL15531347 | 0.82 | BLM (0.41) | MEN1LMNAHPGDTSHRBLM | |
| Foscarnet SCHEMBL8647698 | 0.82 | BLM (0.41) | MEN1LMNAHPGDTSHRBLM | |
| Foscarnet SCHEMBL7822128 | 0.80 | MMP2 (0.43) | MEN1LMNAHPGDTSHRBLM | |
| Foscarnet SCHEMBL11596760 | 0.78 | — | — | |
| Foscarnet SCHEMBL8169999 | 0.78 | BLM (0.39) | MEN1LMNAHPGDTSHRBLM | |
| Water SCHEMBL11452217 | 0.78 | KDM4E (0.50) | MEN1LMNAHPGDTSHRBLM | |
| Foscarnet SCHEMBL5058619 | 0.78 | BLM (0.39) | MEN1LMNAHPGDTSHRBLM | |
| Foscarnet SCHEMBL8854374 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019418-A1 | A NEW CHEMICAL COMPOUND | PERSTORP AB (SE) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997026266-A1 | A NEW CHEMICAL COMPOUND | PERSTORP AB (SE) | 1997-07-24 | — | — | WO | disclosed |