Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436434 | 0.80 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL3174371 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL365038 | 0.71 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL30343873 | 0.69 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL12138536 | 0.69 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL1422494 | 0.68 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL1422492 | 0.68 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL28111509 | 0.67 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL27886351 | 0.67 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL1252770 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066666-A | OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX | WASHINGTON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |