Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.44 |
| ▸ | PI4KA | P42356 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798453 | 0.93 | PIK3CG (0.43) | SMN1; SMN2PIK3CGPI4KARAB9AALDH1A1 | |
| SCHEMBL790487 | 0.93 | PIK3CG (0.47) | PIK3CGPI4KARAB9APIK3C3PIK3CD | |
| SCHEMBL807111 | 0.93 | RAB9A (0.46) | PIK3CGPI4KARAB9AALDH1A1KDM4E | |
| SCHEMBL807023 | 0.91 | PIK3CG (0.49) | PIK3CGPI4KARAB9APIK3C3PIK3CD | |
| SCHEMBL789808 | 0.90 | PIK3CG (0.44) | SMN1; SMN2PIK3CGPI4KARAB9AALDH1A1 | |
| SCHEMBL789741 | 0.87 | PI4KA (0.46) | PIK3CGPI4KARAB9AALDH1A1KDM4E | |
| SCHEMBL806791 | 0.87 | PI4KA (0.43) | SMN1; SMN2PIK3CGPI4KARAB9AALDH1A1 | |
| SCHEMBL807247 | 0.86 | PIK3CG (0.48) | PIK3CGPI4KAPIK3C3PIK3CDPIK3CA | |
| SCHEMBL791568 | 0.85 | PI4KA (0.43) | SMN1; SMN2PIK3CGPI4KARAB9AALDH1A1 | |
| SCHEMBL807161 | 0.84 | PIK3C3 (0.49) | PIK3CGPI4KARAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |