Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777973 | 0.79 | CYP3A4 (0.36) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL4484025 | 0.79 | CYP3A4 (0.36) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL12777971 | 0.76 | ALDH1A1 (0.42) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL8061099 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8061104 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL8075720 | 0.74 | FFAR1 (0.39) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7636313 | 0.74 | ALDH1A1 (0.43) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7636310 | 0.74 | ALDH1A1 (0.43) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7643014 | 0.72 | CHRNB2 (0.37) | CHRNB2CHRNA4MEN1CHRNA7KMT2A | |
| SCHEMBL7643013 | 0.72 | CHRNB2 (0.37) | CHRNB2CHRNA4MEN1CHRNA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021409-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Novartis AG (CH) | 2000-07-26 | — | — | EP | claimed |
| WO-1999012906-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | NOVARTIS AG (CH) | 1999-03-18 | — | — | WO | claimed |
| EP-1021409-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | Novartis AG (CH) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999012906-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | NOVARTIS AG (CH) | 1999-03-18 | — | — | WO | disclosed |